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Table 1 Increased nucleolar association of chromosomes expressing transgenic XIST

From: Impact of flanking chromosomal sequences on localization and silencing by the human non-coding RNA XIST

Integration site % perinuclear % perinuclear % perinuclear % perinucleolar % perinucleolar % perinucleolar
No DOX DOX CHANGE No DOX DOX CHANGE
1p 27 34 7 10 36 16a
3q 78 70 −8 10 18 8
4q 57 74 17b 12 25 14a
7p 32 27 −5 29 47 18a
7q 30 53 23a 28 39 11c
8p 59 39 −21a 29 56 27a
12q 36 39 3 18 35 17a
15q 24 36 14c 46 53 7
Xq23 42 46 5 31 41 10
  1. The numbers shown are based on three independent experiments for the DOX results and one experiment for the No DOX results, with ≥50 cells counted for each integration site in each experiment. Chi-squared test (a P ≤0.001; b P ≤0.01; c P ≤0.05)
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Genome Biology

ISSN: 1474-760X

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