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Fig. 6 | Genome Biology

Fig. 6

From: New genes drive the evolution of gene interaction networks in the human and mouse genomes

Fig. 6

Fraction of topologically and functionally essential genes for gene groups from different divergence times. a Fraction of hub genes in PPI network within gene groups of different divergence times. Hub genes are defined as genes with network connectivity greater than median level (Interaction degree > = 6). Branch assignment is labeled near each data point. The age assignment for each branch follows Fig. 1. The dash line indicates the polynomial regression correlation between divergence times of genes and the fractions of hub genes. b Fraction of essential genes in regards to their PPI network connectivity. The solid line indicates the linear regression correlation between PPI network connectivity of genes and the fractions of essential genes within each gene group. c Fraction of essential genes in PPI network within gene groups from different divergence times. The dash line indicates the polynomial regression correlation between divergence times of genes and the fractions of essential genes

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