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Fig. 5 | Genome Biology

Fig. 5

From: New genes drive the evolution of gene interaction networks in the human and mouse genomes

Fig. 5

Expression breadths of genes in regards to their PPI network connectivity and divergence times. a Average number of tissues with expression of genes with various PPI network connectivity based on RNA-seq expression level data. b Average number of tissues with expression of genes with various PPI network connectivity based on protein expression level data. The error bars show the standard error of the mean for each group of genes, and the solid line indicates the linear regression correlation between network connectivity of genes and their expression breadths. c Average number of tissues with expression of genes from different phylogenetic branches based on RNA-seq expression level data. d Average number of tissues with expression of genes from different phylogenetic branches based on protein expression level data. The dash line indicates the polynomial regression correlation between divergence times of genes and their expression breadths. Branch assignment is labeled near each data point. The age assignment for each branch follows Fig. 1

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