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Fig. 4 | Genome Biology

Fig. 4

From: Spatial reorganization of telomeres in long-lived quiescent cells

Fig. 4

Telomere hyperclusters are a feature of long-lived quiescent cells and require mitochondrial activity. a Colony forming ability measured as percentage of colony forming units (CFU) of WT strain yAT1684 after 7 days in quiescence induced by different methods: carbon exhaustion from YPD (SP); SP respiratory-deficient cells (SP rho-); nitrogen starvation; abrupt starvation of exponential and post-diauxic cells. Cells were plated at day 1 and day 7 after quiescence induction and the ratio day 7/day 1 was considered as the day 7 CLS. Standard deviations from three experiments are indicated. b Representative fluorescent Rap1-GFP images of cultures used for the CFU assay shown in (a). Cells were imaged at day 1 CLS. Pie charts represent the percentage of cells with telomere hyperclusters within the population (black)

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