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Fig. 1 | Genome Biology

Fig. 1

From: Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome

Fig. 1

Unbiased analysis of DNA methylomes in colonic ISCs and their progeny during the suckling period. a Numbers of DMRs identified from the comparisons between either developmental stages (mDMRs, left) or differentiation states (dDMRs, right). Analyses were based on the association of DMRs with non-CGIs (top), and with CGIs (bottom). Black bars indicate methylation gains and white bars indicate methylation losses. b Distribution of mDMRs or dDMRs relative to gene region categories based on RefSeq annotation of all known genes. CGI-associated mDMRs are enriched in the gene body and 3′ end

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