Skip to main content
Fig. 3 | Genome Biology

Fig. 3

From: Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells

Fig. 3

HP1β is important for mesodermal differentiation of embryoid bodies. a Relative fold change of developmental genes of the three germ layers in EBs derived from HP1α KO ESCs (empty bars) and EBs derived from HP1β KO ESCs (filled bars). Upregulated genes are depicted above the line at zero, and downregulated genes below it. The grey area represents fold changes which are not statistically significant. b GO analysis of biological processes affected in HP1β KO EBs. Biological processes where the bars in the graph go to the left of zero are those affected significantly by genes downregulated in HP1β−/− EBs, whereas the those where the bars go to the right of zero are those significantly affected by genes upregulated in HP1β−/− EBs. The actual p values are shown for each biological process. c Relative fold change of key pluripotent factors for EBs derived from HP1β KO ESCs. Upregulated genes are depicted above the line at zero and downregulated genes below it. The grey area represents fold changes which are not statistically significant

Back to article page