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Fig. 2 | Genome Biology

Fig. 2

From: Host genetic variation impacts microbiome composition across human body sites

Fig. 2

Complex disease and functional SNPs are enriched among microbiome-correlated host genetic variation. a Enrichment of genes correlated with microbiome composition (y-axis) compared to all other genes that are significantly associated with a complex disease using a given P value threshold (x-axis). Each colored line represents a different complex disease with an enrichment of at least three-fold. b Enrichment of SNPs correlated with microbiome composition (y-axis) compared to all other SNPs that have been identified as eQTLs in the GTEx data using a given P value threshold (x-axis). Each colored line represents a different tissue type analyzed by GTEx. c Enrichment of SNPs (blue) and genes (red) correlated with microbiome composition in this study (y-axis) among SNPs and genes correlated with microbiome composition in the TwinsUK dataset using a given P value threshold (x-axis)

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