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Table 1 Number of included cancer susceptibility regions and nearby genes for each cancer type investigated

From: Limited evidence that cancer susceptibility regions are preferential targets for somatic mutation

Cancer subtype

GWAS loci

LD genes

Nearby genes

Bladder

12

103

264

Breast

80

702

1324

Cervical

7

148

290

Colon

25

215

421

Endometrial

1

1

18

Glioma

9

90

212

Kidney

5

12

48

Liver

7

89

195

Lung

10

257

350

Multiple myeloma

5

129

219

Ovarian

10

119

213

Prostate

71

697

1583

Skin

14

311

493

Stomach

2

12

24

Thyroid

5

15

40

Total

263

2190

4103

  1. All cancer susceptibility regions have a published p value less than 5 × 10−8, are independent of each other, are associated with cancer in European populations, and were discovered prior to 25 August 2014. Linkage disequilibrium (LD) genes are those within the LD block of the susceptibility variant. Nearby genes are defined as those within the LD block of the susceptibility variant or within 500 kb of the LD block. For the genes, the total is for all unique genes and excludes duplicates across cancer types