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Fig. 8 | Genome Biology

Fig. 8

From: Comparison of Hi-C results using in-solution versus in-nucleus ligation

Fig. 8

Comparison of TAD boundary recognition. Average coverage- and distance-corrected Hi-C interaction profiles around TAD boundaries (top panels). Averaged standard score of the interaction directionality indices around TAD boundaries (line graphs). Venn diagrams of boundaries detected in the datasets as shown. Zoomed in views of randomly selected TADs from mouse chromosome 9 for each category (bottom panels). a TAD boundaries detected in both in-nucleus ligation (INL) and both in-solution ligation (ISL) replicates. b TAD boundaries detected by both ISL replicates only. c TAD boundaries detected by both INL replicates only

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