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Fig. 2 | Genome Biology

Fig. 2

From: The senescent methylome and its relationship with cancer, ageing and germline genetic variation in humans

Fig. 2

DNA methylation is reversed during the reversal of senescence of DS HMECs. a SA-β-gal staining of EP, DS+siGLO and DS+p16siRNA cells. b Quantitation of proliferation (top row), BrdU positivity (middle row), 8-oxoguanine negativity (bottom row) in DS+siGLO and DS+p16siRNA cells at days 2, 5, 7 and 9 post transfection. c A line plot of the beta value difference between each stage of the experiment and the EP cells for each of the hyper-senDMPs (top row) and hypo-senDMPs (bottom row). The thick coloured line in each plot represents the mean of all the hyper-senDMPs or hypo-senDMPs

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