Fig. 3
From: Analysis methods for studying the 3D architecture of the genome
Visualization of Hi-C data. An Epigenome Browser snapshot of a 4 Mb region of human chromosome 10. Top track shows Refseq genes. All other tracks display data from the human lymphoblastoid cell line GM12878. From top to bottom these tracks are: smoothed CTCF signal from ENCODE [130]; significant contact calls by Fit-Hi-C using 1 kb resolution Hi-C data (only the contacts >50 kb distance and − log(p-value) ≤25 are shown) [20]; arrowhead domain calls at 5 kb resolution [18]; Armatus multiscale domain calls for three different values of the domain-length scaling factor γ [87]; DI HMM TAD calls at 50 kb resolution [15]; and the heatmap of 10 kb resolution normalized contact counts for GM12878 Hi-C data [18]. The color scale of the heatmap is truncated to the range 20 to 400, with higher contact counts corresponding to a darker color