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Fig. 8 | Genome Biology

Fig. 8

From: Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data

Fig. 8

Relationship between long-range correlations, GC content and methylation levels for the 450 k-EBV dataset. Only open sea probes were included in the analysis. a Long-range correlations of the methylation levels stratified by probe GC content. b Same as (a), but GC content was measured in a 1-kb window around the probe. c Long-range correlations of the methylation levels stratified by average probe methylation. d Relationship between mean methylation level and GC content. While regions with high GC content tend to have low methylation, for instance CpG islands, we do not observe any relationship between the GC content of the open sea probes and the long-range correlations. We conclude that GC content is not a bias of our methylation correlation analysis

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