Fig. 16

scATAC-seq data. Data from a single experiment on a mixture of the GM12878 and HL60 cell lines described in [13]. a ENCODE DNAse-seq data were used to define hypersensitive sites (DHSs) specific to these two cell lines. For each of these two sets of sites, we computed the average number of ATAC-seq reads normalized by the total number of reads mapped to known DHS sites. The figure shows two distinct clusters; we arbitrarily selected the line y=x/3 to delineate cells from the GM12878 cell line (red points); this defines the scATAC-EBV data containing 2677 cells. b Estimated compartments on chromosome 14 at a resolution of 100 kb using the HiC-EBV-2014 data. c Estimated compartments for the scATAC-EBV data. d Density of correlations for scATAC-EBV. We observe that the three different types of correlations have different distributions. Closed–closed correlations are skewed towards negative values, while open–open correlations are shifted towards positive values