Fig. 4

Analysis of the Rao2014 dataset. a Workflow for identifying hubs from the raw interaction matrix. b Comparison between the Rao2014 and Jin2013 datasets. Genome browser snapshots showing two hubs adjacent to the LIN28A locus (indicated by red and blue respectively) and their associated targets in each dataset are shown. c Prediction accuracy for the Rao2014 IMR90 hubs. The ROC curves correspond to the testing data. AUC scores are shown in parentheses. d Prediction accuracy for applying the Rao2014 IMR90 model to predict hubs in other datasets (Jin2013) or cell-types (GM12872(Rao2014) and K562 (Rao2014)). The ROC curves correspond to the testing data. AUC scores are shown in parentheses