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Fig. 7 | Genome Biology

Fig. 7

From: Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions

Fig. 7

BORIS bound regions correlate with histone retention in human and mouse sperm. a Gene tracks show the distribution of histones retained in human sperm in association with CTCF and BORIS bound regions, mapped in K562, Delta47 and OVCAR8 cell lines. The name of the molecules against which antibodies were directed and the cell lines used in ChIP-seq are shown on the left. b Heatmap indicates the enrichment of histones retained in human sperm at 2xCTS regions (invariant BORIS binding in K562, OVCAR8, and Delta47). c, d Average tag density (tags/10 million) of histones retained in human (c) and mouse (d) sperm across BORIS-only (blue), CTCF-only (red) and CTCF&BORIS (purple) bound regions mapped in K562 cells (c) and mouse round spermatids (d). The data were normalized to the number of mapped reads and binding regions

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Genome Biology

ISSN: 1474-760X

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