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Fig. 7 | Genome Biology

Fig. 7

From: Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

Fig. 7

Model of how Crx mutation-caused gene expression changes affect rod and cone development. The left panel describes the formation of cones in a subset of the Crx mutants and variable levels of those cells’ expression of phototransduction genes. The right panel shows how development of rods in all models is related to their gene expression changes. It also emphasizes the novel findings that Crx mutant rods display a graded phenotype of both the decreased expression of proper rod genes, and the mis-expression of cone genes

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Genome Biology

ISSN: 1474-760X

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