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Fig. 2 | Genome Biology

Fig. 2

From: Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

Fig. 2

RNA-seq analyses describe overlapping sets of affected genes in P10 homozygous Crx mutant retinas. a, b Gene expression (log2 CPM) in the indicated homozygous mutants (y-axes) is compared with the WT control (C57BL/6 J, x-axes). Prototypical photoreceptor transcripts are labeled in white. White diagonal lines represent ±2 FC. c, d Venn diagrams illustrate the numbers of significantly affected genes that are shared or are uniquely changed in indicated mutants (FC ≥ 2 or ≤ -2, FDR ≤ 0.05)

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