Fig. 1

Identifying RER in breast tumors and cancer cell lines. a, c Transcription correlation score (TCS) maps for chromosomes 3 and 16 using data from breast tumors [22] (a) and breast cancer cell lines [20] (c). The horizontal dotted line indicates the significance threshold. Arrows indicate regions containing genes with significant TCSs. b Boxplots showing the distribution of TCSs generated for all genes and for RER genes using two independent breast tumor datasets [22, 23]. d Ideograms showing the location of the 45 RER regions identified in breast tumors (red) and the 71 RER regions identified in breast cancer cell lines (blue)