Fig. 3
Genome-wide hypomethylation and hypermethylation correlate weakly. For each cancer type (BRCA breast cancer, BLCA bladder cancer, COAD colon adenomacarcinoma, HNSC head and neck squamous carcinoma, KIRC kidney renal carcinoma, LIHC liver hepatocellular carcinoma, LSCC lung squamous cell carcinoma, LUAD lung adenomacarcinoma, THCA thyroid cancer, UCEC uterine cervix endometrial carcinoma), we display two-dimensional density plots (bright yellow indicates highest density) illustrating the distribution of tumors in the plane defined by the HyperZ and HypoZ indices. The number of tumors is given above each panel. For each cancer type, we provide the Spearman correlation coefficient (SCC), its P value, as well as the R2 value for a linear regression