Skip to main content
Fig. 2 | Genome Biology

Fig. 2

From: Dynamics of gene silencing during X inactivation using allele-specific RNA-seq

Fig. 2

X-linked gene expression during differentiation of ES_Tsix-stop ESCs towards EBs and in NPCs. a Tsix / Xist expression dynamics during XCI in ES_Tsix-stop ESCs by EB differentiation, as well as in NPCs. Genome browser view of the Tsix/Xist locus, and the percentage of cells positive for Xist clouds as determined by RNA-FISH. b Total Xist expression levels in RPKM (corresponding to (a); in black), as well as the contribution from the 129-derived (green) or Cast-derived (blue) alleles. c Distribution of gene expression in male (E14; blue) and female (ES_Tsix-stop; pink) ESCs during EB formation. All genes with an expression level of RPKM >0.5 in at least one condition are included (542 and 13,819 genes on the X chromosome and autosomes, respectively)

Back to article page