Fig. 5From: Extensive rewiring of epithelial-stromal co-expression networks in breast cancerComparative functional network enrichment analysis of the epithelial-stromal versus epithelial-epithelial co-expression networks in normal breast, ER-positiveIBC, and ER-negativeIBC. a–c Scatterplots in which each point is a functional geneset plotted according to its statistical significance in the epithelial-epithelial co-expression network (y-axis) and the epithelial-stromal co-expression network (x-axis) in normal breast, ER-positive IBC, and ER-negative IBC. Terms are colored as in Fig. 4. A subset of top-ranking genesets is labeled in the plots. d–f Venn diagrams of genesets identified as significantly enriched (FDR < 5 %) in epithelial-epithelial and/or epithelial-stromal co-expression networks in normal breast, ER-positive IBC, and ER-negative IBC, respectively. EE epithelial-epithelial; ER estrogen receptor; ES epithelial-stromal; IBC invasive breast cancer; Neg negative; Norm normal; Pos positive Back to article page