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Table 2 Summary of ZFP57 binding within ICRs

From: Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression

Chr Start End Gene ChIP-seq peaks TGCCGCR motif TGCCGCY motif ChIP-seq allele SNP-Pyro allele
1 63246657 63247300 Gpr1 1 1 2 Mat Mat
1 63305566 63315360 Zdbf2 - - 2 - -
2 157385609 157387535 Nnat/Peg5 1 4 2 N/A ND
2 152512421 152513169 Mcts2 1 3 - Mat ND
2 174119863 174126564 Gnas_ProXL 2 7 7 Mat Mat
2 174150877 174154638 Gnas_Ex1A - - 4 - -
5 135825859 135825980 Fkbp6 1 1 - Bi Bi
6 4696743 4699483 Peg10 1 3 - N/A ND
6 30684932 30689966 Mest 3 8 4 Mat ND
6 58856396 58857391 Nap1l5 1 4 1 N/A ND
7 67147381 67151583 Snrpn 3 9 1 Mat Mat
7 6679787 6684257 Peg3 2 7 1 Mat Mat
7 135830870 135832249 Inpp5f_v2 2 6 - Mat ND
7 149764673 149771930 Igf2/H19 1 5 1 N/A Pat
7 150480736 150482810 KvDMR1 1 3 - Mat Mat
8 125387861 125390344 Cdh15 1 2 - Bi ND
9 89767090 89775128 Rasgrf1 1 5 4 N/A Pat
10 12809697 12812131 Zac1 1 6 - Mat Mat
12 110762703 110773093 IG-DMR 1 8 2 Pat Pat
11 11925127 11927100 Grb10 1 3 1 Mat Mat
11 22871610 22874212 Zrsr1 2 - 2 Mat ND
15 72639707 72641342 Peg13 3 5 - Mat ND
17 12934169 12935816 Igf2r 4 7 1 Mat ND
18 13130435 13133510 Impact 2 5 - Mat ND
  1. For each locus, the number of ZFP57 ChIP-seq peaks, underlying TGCCGCR/Y binding motifs and allele-specificity are shown. Start and end points of germline DMRs are taken from [31, 32, 40]. All coordinates are NCBI/mm9 genome assembly. Bi biallelic Zfp57 binding at Cdh15 DMR consistent with biallelic methylation reported in ES cells [40], Mat maternal, N/A no available SNPs to distinguish allele specificity, ND pyrosequencing assay not conducted for this locus, Pat paternal