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Table 2 Summary of ZFP57 binding within ICRs

From: Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression

Chr

Start

End

Gene

ChIP-seq peaks

TGCCGCR motif

TGCCGCY motif

ChIP-seq allele

SNP-Pyro allele

1

63246657

63247300

Gpr1

1

1

2

Mat

Mat

1

63305566

63315360

Zdbf2

-

-

2

-

-

2

157385609

157387535

Nnat/Peg5

1

4

2

N/A

ND

2

152512421

152513169

Mcts2

1

3

-

Mat

ND

2

174119863

174126564

Gnas_ProXL

2

7

7

Mat

Mat

2

174150877

174154638

Gnas_Ex1A

-

-

4

-

-

5

135825859

135825980

Fkbp6

1

1

-

Bi

Bi

6

4696743

4699483

Peg10

1

3

-

N/A

ND

6

30684932

30689966

Mest

3

8

4

Mat

ND

6

58856396

58857391

Nap1l5

1

4

1

N/A

ND

7

67147381

67151583

Snrpn

3

9

1

Mat

Mat

7

6679787

6684257

Peg3

2

7

1

Mat

Mat

7

135830870

135832249

Inpp5f_v2

2

6

-

Mat

ND

7

149764673

149771930

Igf2/H19

1

5

1

N/A

Pat

7

150480736

150482810

KvDMR1

1

3

-

Mat

Mat

8

125387861

125390344

Cdh15

1

2

-

Bi

ND

9

89767090

89775128

Rasgrf1

1

5

4

N/A

Pat

10

12809697

12812131

Zac1

1

6

-

Mat

Mat

12

110762703

110773093

IG-DMR

1

8

2

Pat

Pat

11

11925127

11927100

Grb10

1

3

1

Mat

Mat

11

22871610

22874212

Zrsr1

2

-

2

Mat

ND

15

72639707

72641342

Peg13

3

5

-

Mat

ND

17

12934169

12935816

Igf2r

4

7

1

Mat

ND

18

13130435

13133510

Impact

2

5

-

Mat

ND

  1. For each locus, the number of ZFP57 ChIP-seq peaks, underlying TGCCGCR/Y binding motifs and allele-specificity are shown. Start and end points of germline DMRs are taken from [31, 32, 40]. All coordinates are NCBI/mm9 genome assembly. Bi biallelic Zfp57 binding at Cdh15 DMR consistent with biallelic methylation reported in ES cells [40], Mat maternal, N/A no available SNPs to distinguish allele specificity, ND pyrosequencing assay not conducted for this locus, Pat paternal