Figure 4

Regions with variable structure are less successfully modeled and are associated with cell-type-specific enhancer activity.(A) Model accuracy is significantly different between low- and high-variability regions, defined as, respectively, the lowest and highest thirds of the distribution of median absolute deviations between cell types. (B) Regions occupying altered compartments are defined as those assigned to A in one cell type but to B in the other two cell types, or vice versa. The numbers of enhancers (cell type specific or shared between two or more cell types) are shown for regions with altered (open or closed) and non-altered (none) compartments in each cell type. PCC, Pearson correlation coefficient.