Skip to main content

Table 7 Comparison of Fly-FISH localization patterns enriched among BRAT-associated mRNAs and mRNAs upregulated in brat mutant embryos in Classes A, B, and C

From: Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition

  All BRAT-associated mRNAs mRNAs associated only with BRAT PUM and BRAT co-target mRNAs mRNAs upregulated in brat mutant embryos
Class A Class B Class C
Embryonic stages 1 to 3 localization patterns
Posterior localization ++ . ++ . . .
Nuclei-associated/Perinuclear ++ . ++ . . ++++
Embryonic stages 4 to 5 localization patterns
Patterns indicative of zygotic transcription . . + . . .
Pole cell enrichment + . . . +++ +
Yolk plasm localization . + . . . .
  1. + FDR = 1% to 10%; ++ FDR = 0.1% to 1%; +++ FDR = 0.001% to 0.1%; ++++ FDR = 10−5% to 0.001%; +++++ FDR <10−5%; ‘.’ = not significant (FDR >10%). FDR values indicated represent the most significantly enriched term related to the localization pattern listed. For details see Additional files 9 and 17.