Skip to main content

Table 7 Comparison of Fly-FISH localization patterns enriched among BRAT-associated mRNAs and mRNAs upregulated in brat mutant embryos in Classes A, B, and C

From: Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition

 

All BRAT-associated mRNAs

mRNAs associated only with BRAT

PUM and BRAT co-target mRNAs

mRNAs upregulated in brat mutant embryos

Class A

Class B

Class C

Embryonic stages 1 to 3 localization patterns

Posterior localization

++

.

++

.

.

.

Nuclei-associated/Perinuclear

++

.

++

.

.

++++

Embryonic stages 4 to 5 localization patterns

Patterns indicative of zygotic transcription

.

.

+

.

.

.

Pole cell enrichment

+

.

.

.

+++

+

Yolk plasm localization

.

+

.

.

.

.

  1. + FDR = 1% to 10%; ++ FDR = 0.1% to 1%; +++ FDR = 0.001% to 0.1%; ++++ FDR = 10−5% to 0.001%; +++++ FDR <10−5%; ‘.’ = not significant (FDR >10%). FDR values indicated represent the most significantly enriched term related to the localization pattern listed. For details see Additional files 9 and 17.