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Table 2 Summary of Fly-FISH localization patterns enriched among BRAT- and PUM-associated mRNAs

From: Brain tumor is a sequence-specific RNA-binding protein that directs maternal mRNA clearance during the Drosophila maternal-to-zygotic transition

  All PUM-associated mRNAs mRNAs associated only with PUM All BRAT-associated mRNAs mRNAs associated only with BRAT PUM and BRAT co-target mRNAs
Embryonic stages 1 to 3 localization patterns
Posterior localization + . ++ . ++
Nuclei-associated/Perinuclear + . ++ . ++
Embryonic stages 4 to 5 localization patterns
Segmented/Gap-gene localization +++ +++ . . .
Patterns indicative of zygotic transcription +++++ ++++ . . +
Perinuclear around yolk nuclei + + . . .
Cell division apparatus + + . . .
Apical enrichment + + . . .
Pole cell enrichment . . + . .
Yolk plasm localization . . . + .
  1. + FDR = 1% to 10%; ++ FDR = 0.1% to 1%; +++ FDR = 0.001% to 0.1%; ++++ FDR = 10−5% to 0.001%; +++++ FDR <10−5%; ‘.’ = not significant (FDR >10%). FDR values indicated represent the most significantly enriched term related to the localization pattern listed. For details see Additional file 9.