Figure 1
From: Domain atrophy creates rare cases of functional partial protein domains
Schematic representation of domain atrophy event. A protein domain in a particular architecture undergoes truncation due to mutation. A protein with truncated domain that retains its functional role (structural or enzymatic) is positively selected, while a protein with non-viable truncated domain is lost. Complete and incomplete domain boundaries are denoted by smooth and toothed edges, respectively. The dotted line in the toy example at the right shows the region of upstream domain-bounded atrophy.