Figure 3
From: Cis-regulatory somatic mutations and gene-expression alteration in B-cell lymphomas
Local SNV mutation rates for TFBSs and protein-coding exons. Mutation rates are plotted for TFBSs and exons (x-axis) versus their 1-kb flanking regions on both sides (y-axis). Each sample from cohort 1 (A) and cohort 2 (B) is represented by a square for mutation rates in TFBSs (and their flanking regions) and a triangle for mutation rates in exons (and their flanking regions). Tumor subtypes are color-coded (see legend) like in Figure 1. Results are for SNVs. Figures corresponding to local indel mutation rates are provided in Additional file 1: Figure S3. DLBCL, diffuse large B-cell lymphoma; FL, follicular lymphoma; PMBCL, primary mediastinal large B-cell lymphoma; SNV, single nucleotide variant; TFBS, transcription factor binding site.