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Figure 7 | Genome Biology

Figure 7

From: Denoising perturbation signatures reveal an actionable AKT-signaling gene module underlying a poor clinical outcome in endocrine-treated ER+ breast cancer

Figure 7

The AKT clique gene module. List of genes making up the 31-gene AKT clique module used to estimate AKT perturbation activity. Colors indicate whether they are up- or downregulated in response to AKT activation. We indicate in bold those genes that have been reported to have tumor suppressor roles in cancer. The two genes upregulated in the perturbation signature are members of the EndoPredict assay. Diff.

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