Figure 1

Increased levels of poly(A) + Y1 RNA in RRMS. (A) Total Y RNA levels in peripheral whole blood determined after cDNA synthesis using random hexamers in CTRL (N = 24) and RRMS (N = 22). (B) As in (A) except oligo-dT was used for cDNA synthesis. (C) As in (B) except different disease cohorts. Individual transcripts were normalized to GAPDH transcript levels in CTRL (N = 24), SLE (N = 24), RA (N = 18), NMO (N = 22), and PD (N = 19). (D) Total poly(A) + Y1 RNA levels were determined using oligo-dT in CTRL (N = 24), CIS-MS (N = 16), RRMS-NAÏVE (N = 24), and RRMS (N = 22). Error bars are S.D. *P <0.05, **P <0.005.