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Figure 4 | Genome Biology

Figure 4

From: Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming

Figure 4

Effect of EDs on allele-specific expression of imprinted genes in fetuses derived from exposed prospermatogonia. Experimental design was as in Figure 3A. Results of RNA Sequenom allelotyping experiments of imprinted transcripts) are shown using the color scale as in Figure 2C; ‘(a)’ and ‘(b)’ denote independent SNPs in the same transcript. Average (n = 3) parental allele-specific transcription is displayed. Note the overall undisturbed allele-specific transcription. Statistically significant (P <0.05) differences between ED and control greater than 5% are indicated by thin rectangles. More groups of fetuses are shown in Additional file 2.

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