Figure 5

Receiver operating characteristic curve comparisons of methods that detect mutually exclusive alterations for simulated datasets. (a) Comparison with the large dataset. (b) Comparison with the small dataset. (c) Comparison of methods that do search space reduction (Mutex and MEMo) after ensuring all seeded groups are in the reduced search space of both methods. (d, e) Comparisons after removing the search space reduction of Mutex, for large and small datasets.