Table 1 KEGG functions enriched for genes correlated with AGS

Metabolism

A

Positive

Metabolism of cofactors and vitamins

B

Positive

Amino acid metabolism

B

Positive

Carbohydrate metabolism

B

Positive

Glycan biosynthesis and metabolism

B

Positive

Two-component system

C

Positive

Biosynthesis of amino acids

C

Positive

Glycosaminoglycan degradation

C

Positive

Pentose and glucuronate interconversions

C

Positive

Lipopolysaccharide biosynthesis

C

Positive

Histidine metabolism

C

Positive

Fructose and mannose metabolism

C

Positive

Carbon metabolism

C

Positive

Alanine, aspartate and glutamate metabolism

C

Positive

Biotin metabolism

C

Positive

Membrane transport

B

Negative

Drug resistance

B

Negative

Peptidoglycan biosynthesis

C

Negative

ABC transporters

C

Negative

Pyruvate metabolism

C

Negative