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Figure 4 | Genome Biology

Figure 4

From: Average genome size estimation improves comparative metagenomics and sheds light on the functional ecology of the human microbiome

Figure 4

Estimation accuracy in the presence of microbial eukaryotes and viruses. (A) MicrobeCensus was used to estimate the AGS of 20 simulated 100-bp metagenomes that contained up to 50% of Fungi, representing up to 94% of total reads. Note that axes are plotted on a log scale. (B) MicrobeCensus was used to estimate the AGS of 20 simulated 100-bp metagenomes that contained up to 50% of reads from viruses. Signed error is defined as: (AĜS - AGS)/AGS. (C) AGS estimates from (B) were used to estimate the total coverage of microbial genomes present in the simulated metagenomes. Estimated coverage of microbial genomes was obtained by dividing the number of total base pairs in a metagenome by the estimated AGS for that metagenome.

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