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Figure 6 | Genome Biology

Figure 6

From: MUSiCC: a marker genes based framework for metagenomic normalization and accurate profiling of gene abundances in the microbiome

Figure 6

The impact of MUSiCC on the discovery of differentially abundant genes. The number of genes identified as differentially abundant between (A) HMP stool samples and tongue dorsum samples, (B) type 2 diabetes (T2D) cases and controls, and (C) inflammatory bowel disease (IBD) cases and controls, are illustrated. Each Venn diagram describes the overlap between the set of genes identified when using standard compositional normalization (cyan, left) and the set of genes identified when using MUSiCC (maroon, right). Pathways that are over-represented in the set of genes identified by only one of the two methods are listed.

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Genome Biology

ISSN: 1474-760X

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