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Figure 6 | Genome Biology

Figure 6

From: 5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer

Figure 6

5hmC marked promoters are not subject to histone-bivalency-mediated methylation gain. Venn diagrams to illustrate a high incidence of promoter methylation gain in our cohort at promoters with H3K4me3/K27me3 bivalency in human embryonic stem cells (hESCbiv). The incidence of methylation gain is low at hESCbiv promoters marked by 5hmC in normal colon. (a) For narrow and (b) broad 5hmC promoters.

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