Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

Table 1 Clinical parameters of metastatic melanoma patients

Clinical parameter	SOX9 low	SOX9 high	p value
T0	15	13	0.706
T1	2	11	0.013	*
T2	17	17	1
T3	20	13	0.223
T4	16	16	1
N0	26	44	0.031	*
N1	16	9	0.162
N2	15	9	0.221
N3	12	9	0.513
NX	1	0	1
M0	67	64	0.793
M1	2	6	0.157
Female	29	25	0.586
Male	45	49	0.68
Lymph node	48	49	0.919
Regional cutaneous or subcutaneous metastasis	17	14	0.59
Distant metastasis	9	11	0.655
Age	57	59.9	0.213^a

TNM stage, gender, and tumor location between the SOX9 high and SOX9 low patients were evaluated by the Chi-squared test.
^aAge was evaluated by Student’s t-test.
*P <0.05.

ISSN: 1474-760X