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Table 4 Sibling sex ratios of families with probands with SD or non-SD AIDs

From: Copy number variation in Y chromosome multicopy genes is linked to a paternal parent-of-origin effect on CNS autoimmune disease in female offspring

Autoimmune disease Sexual dimorphism Male Female Sex ratio
Multiple sclerosis F > M    
  Jorge Oksenberg (personal communication) 531 1,356 0.39
  Bertrand Fontaine (personal communication) 252 405 0.62
  Sawcer et al. [35] 190 388 0.49
  Ebers et al. [36] 220 366 0.6
Systemic lupus erythematosus F > M    
  Aggarwal et al. [5] 3,201 5,434 0.59
  Moorthy et al. [4] 115 181 0.64
Rheumatoid arthritis F > M    
  Lindsey Criswell (personal communication) [37] 987 1,633 0.6
  Peter Gregersen (NARAC) 2,032 3,087 0.66
Pauciarticular onset juvenile arthritis F > M 62 114 0.54
  Moorthy et al. [4]
Systemic onset juvenile arthritis     
  Moorthy et al. [4] F = M 32 32 1
Type 1 diabetes F = M    
  Patrick Concannon (personal communication) 1,589 1,489 1.07
  John Todd (personal communication) 3,707 3,627 1.07
  1. F, female; M, male.