Skip to main content

Table 3 Enriched (FDR ≤ 0.1) inferred functions among all the differentially expressed lncRNAs (DE lncRNAs) and differentially expressed novel lncRNAs (DE novel lncRNAs) in psoriatic skin

From: Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin

Enrichment   No. of genes with the function No. of DEGs with the function P value FC FDR
DE lncRNAs (total) Cytokine activity 42 41 5.28E-12 1.91 3.72E-08
Extracellular space 69 60 4.96E-11 1.70 3.50E-07
Extracellular region part 87 72 7.77E-11 1.62 5.48E-07
Cellular lipid metabolic process 68 56 1.78E-08 1.61 1.25E-04
Fatty acid metabolic process 42 37 1.50E-07 1.72 1.05E-03
Lipid metabolic process 87 66 4.21E-07 1.48 2.96E-03
Monocarboxylic acid metabolic process 46 39 6.41E-07 1.66 4.51E-03
Lipid biosynthetic process 45 38 1.11E-06 1.65 7.80E-03
Regulation of inflammatory response 23 22 1.90E-06 1.87 1.34E-02
Cytokine receptor interaction 34 30 2.18E-06 1.73 1.54E-02
DE novel lncRNAs Extracellular space 69 30 3.99E-07 2.33 1.32E-03
Extracellular region part 87 34 1.42E-06 2.09 4.72E-03
Cytokine activity 42 20 6.80E-06 2.55 2.26E-02
Cellular lipid metabolic process 68 27 1.34E-05 2.13 4.46E-02
Lipid metabolic process 87 32 1.42E-05 1.97 4.72E-02
Biosynthesis of unsaturated fatty acid 6 6 1.97E-05 5.36 6.54E-02
Exidoreductase activity 48 21 2.14E-05 2.34 7.09E-02
  1. FC refers to the observed to expected ratios for the enrichment. For illustration purposes, only inferred functions annotated with at most 100 genes are shown.