Table 6 mRNA expression and DNA methylation in subcutaneous adipose and omentum
Gene | Adipose tissue | log2 fold change expression before vs. after weight loss | T statistic | P value | ∆ DNA methylation before vs. after weight loss | Methylation probe location |
|---|---|---|---|---|---|---|
ACACA | Subcutaneous | −0.82 | 4.02 | 0.001 | −0.17 | 5′ UTR |
CETP | Subcutaneous | −2.48 | 5.49 | 0.00008 | 0.15 | TSS1500 |
CTGF | Subcutaneous | 0.94 | 3.72 | 0.002 | 0.14, 0.12 | TSS1500 |
S100A8 | Subcutaneous | 2.49 | 4.46 | 0.0005 | −0.12 | 5′UTR |
S100A9 | Subcutaneous | 2.23 | 4.18 | 0.0009 | −0.12 | 5′UTR |
PLIN4 | Omentum | 0.89 | 4.86 | 0.0002 | 0.04 | TSS200 |