Figure 3

Direct pairwise comparisons between RIP-seq experiments for each of the closed loop components and 4E-BPs. (A) Scatterplots display change in the log₂ median fold changes (IP/Total) for each of the six proteins compared with one another. Highlighted in red are those transcripts identified as being significantly different between the two experiments according to edgeR's interaction GLM model at a FDR <0.05. (B) Table depicting the total numbers of transcripts that vary significantly across the pairwise comparisons in (A). The numbers represent transcripts that are over-represented in the IPs of proteins listed in the columns relative to proteins listed in each row.