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Figure 3 | Genome Biology

Figure 3

From: MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

Figure 3

MAGeCK is robust against sequencing depth and the number of targeting sgRNAs per gene. (a) The number of significantly selected sgRNAs and genes in the leukemia dataset using various sequencing depths. The maximum sequencing depth for all samples is 30 million. See Materials and methods for sampling details. (b) The number of significantly selected sgRNAs and genes in the melanoma dataset using various sequencing depths. The maximum sequencing depth for all samples is 17.5 million. See Materials and methods for sampling details. Error bars represent the standard deviation from three independent sampling experiments.

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Genome Biology

ISSN: 1474-760X

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