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Table 3 Possible candidate genes for QTLs affecting microbiome and body weight/composition traits in the G 10 mice

From: Host genetics and diet, but not immunoglobulin A expression, converge to shape compositional features of the gut microbiome in an advanced intercross population of mice

Chrom

Microbiome trait

Position (Mb)

CI (Mb)

Body trait

Position (Mb)

Candidate gene(s)

Position (Mb)

5

OTU3615

115.2

112.9-118.1

% Fat

116.6

Pla2g1b

115.4

Nos1

117.8-117.9

9

Lactococcus lactis

113.3

112.3-115.0

Weight

112.3

Glb1

114.4

11

OTU22207

97.8

93.4-114.0

% Lean and % Fat

105.1 and 107.3

Igf2bp1

96.0

Gast

100.3

Pyy

102.1

18

OTU30840

68.4

65.4-70.2

Weight, % Lean and % Fat

69.1 and 69.6

Mc4r

66.9

  1. For each of four chromosomes (Chrom), the positions in Mb are shown for QTLs affecting microbiome abundances and body weight and composition traits as well as possible candidate genes for these QTLs. The confidence intervals (CI) also are given for the QTLs affecting the microbiome traits.