Figure 5
From: Transcriptome-wide modulation of splicing by the exon junction complex
EJC-dependent alternative splicing is linked with transcription. (A) Western blot of control and eIF4A3 KD cells treated with different concentration of transcription elongation inhibitors (DRB, FP and CPT) for 16 h. GAPDH is used as a control. (B) RT-PCR of splicing patterns of representative exons in cells treated with different inhibitors. The quantification of triplicate experiments are shown below as mean ± SD. *P <0.05; **P <0.01; ***P <0.001, one-way ANOVA.