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Table 2 Amino acid substitutions that are the predominant change in the virus population analysed during an individual passage

From: Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity

NP          
  191 323 414 566      
EBOV W V L N      
P1 R D R N      
P2 ? V L S      
P3 W V L S      
P4 W V L S      
P5 W V L S      
VP35          
  129 204 246       
EBOV S N I       
P1 P D A       
P2 S D I       
P3 S D I       
P4 S D I       
P5 S D I       
VP40          
  15 66 259       
EBOV E P M       
P1 Q S M       
P2 ? P R       
P3 E P M       
P4 E P M       
P5 E P M       
  sGP         
sGP/GP GP         
  1 11 49 92 187 203 465 493 638
EBOV M R D V P V I S R
P1 ? ? ? L P ? T S K
P2 K ? ? V L I I P R
P3 M H N V P I I S R
P4 M R N V P I I S R
P5 M R N V P I I S R
sGP/GP GP         
  652 668        
EBOV Y Y        
P1 Y Y        
P2 F C        
P3 Y Y        
P4 Y Y        
P5 Y Y        
VP30          
  214 248        
EBOV L Q        
P1 P ?        
P2 L R        
P3 L Q        
P4 L Q        
P5 L Q        
VP24          
  26 29 43 218      
EBOV L F A K      
P1 F V P R      
P2 F F A ?      
P3 F F A K      
P4 F F A K      
P5 F F A K      
L          
  30 38 161 525 537 538 669 705 707
EBOV G N R N K L I M G
P1 ? ? W N R P ? ? ?
P2 G N R N K L S ? ?
P3 W N R D K L I T ?
P4 ? ? R N K L I M G
P5 G K R N K L I M A
L          
  826 868 879 930 940 943 993 1096 1271
EBOV S S F T L I T L Y
P1 Y S ? ? ? ? ? ? ?
P2 S S F T L I A S Y
P3 S S F T L I T L Y
P4 S P L T L R T L Y
P5 S S F A P I T L STOP
L          
  1308 1478 1546 1733 1763 1949 1998 2144 2151
EBOV S N A F L H S N F
P1 ? ? ? ? ? ? ? N -
P2 P I A F L Q S N V
P3 S N A F L H S N V
P4 S N A Y P ? ? N V
P5 ? H E F L H T K V
L          
  2197         
EBOV L         
P1 -         
P2 L         
P3 L         
P4 P         
P5 L