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Figure 3 | Genome Biology

Figure 3

From: Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis

Figure 3

Relationship between mRNA and protein expression of orthologous transcripts. (A) Scatterplot illustrating the relationship in baseline (0 hpi) mRNA expression as log10 normalized fragments per kilobase of transcript per million mapped reads (FPKM) for all ortholog transcripts (identity >70%). Pearson’s correlation coefficient is indicated in the top right hand corner. (B) Scatterplot matrix of the correlation between transcript expression (log2-fold change) at 8 and 24 hpi in PaKiT03 and HEK293T cells. Pearson’s correlation coefficients are given in upper boxes. Simple linear regression models were fitted and are illustrated as red lines through each scatterplot. (C) Scatterplot matrix of the correlation between protein expression (log10 SILAC ratio) at 8 and 24 hpi in PaKiT03 and HEK293T cells. Pearson’s correlation coefficients are given in the upper boxes. Simple linear regression models were fitted and are illustrated as red lines through each scatterplot. (D) Heatmap of orthologous transcripts that were significantly differentially expressed at 8 and/or 24 hpi in either cell line. Expression values for transcripts are given as log2-fold change.

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