Algorithm | Direction | End point | Gene set | Microarray data | RNA-Seq data | T-index | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Accuracy | AUC | Accuracy | AUC | |||||||||
Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | |||||
k-NN | Forward | Sex | A | 0.988 | 0.988-0.988 | 0.987 | 0.987-0.987 | 0.977 | 0.977-0.977 | 0.977 | 0.977-0.977 | 0.977 |
B | 0.978 | 0.942-0.988 | 0.978 | 0.945-0.987 | 0.869 | 0.523-0.988 | 0.857 | 0.481-0.987 | 0.851 | |||
Cyto Risk | A | 0.939 | 0.895-0.988 | 0.884 | 0.805-0.993 | 0.916 | 0.837-0.977 | 0.825 | 0.68-0.979 | 0.917 | ||
B | 0.931 | 0.837-0.977 | 0.890 | 0.69-0.986 | 0.914 | 0.837-0.965 | 0.903 | 0.736-0.979 | 0.914 | |||
Reverse | Sex | A | 0.895 | 0.895-0.895 | 0.885 | 0.885-0.885 | 0.988 | 0.988-0.988 | 0.987 | 0.987-0.987 | 0.896 | |
B | 0.512 | 0.419-0.593 | 0.503 | 0.426-0.58 | 0.508 | 0.407-0.593 | 0.509 | 0.409-0.6 | 0.510 | |||
Cyto Risk | A | 0.920 | 0.866-0.988 | 0.864 | 0.736-0.993 | 0.949 | 0.837-0.988 | 0.916 | 0.822-0.993 | 0.921 | ||
B | 0.447 | 0.186-0.849 | 0.609 | 0.5-0.802 | 0.850 | 0.767-0.919 | 0.747 | 0.587-0.896 | 0.425 | |||
NSC | Forward | Sex | A | 0.988 | 0.988-0.988 | 0.987 | 0.987-0.987 | 0.978 | 0.977-0.988 | 0.978 | 0.977-0.987 | 0.978 |
 | B | 0.982 | 0.977-0.988 | 0.981 | 0.977-0.987 | 0.988 | 0.988-0.988 | 0.987 | 0.987-0.987 | 0.988 | ||
Cyto Risk | A | 0.931 | 0.872-0.953 | 0.840 | 0.656-0.899 | 0.927 | 0.86-0.977 | 0.828 | 0.649-0.962 | 0.927 | ||
B | 0.884 | 0.826-0.919 | 0.843 | 0.676-0.923 | 0.888 | 0.872-0.892 | 0.885 | 0.815-0.912 | 0.888 | |||
Reverse | Sex | A | 0.977 | 0.977-0.977 | 0.974 | 0.974-0.974 | 0.988 | 0.988-0.988 | 0.987 | 0.987-0.987 | 0.977 | |
B | 0.523 | 0.442-0.558 | 0.502 | 0.472-0.553 | 0.508 | 0.442-0.558 | 0.486 | 0.438-0.539 | 0.516 | |||
Cyto Risk | A | 0.906 | 0.837-0.965 | 0.788 | 0.635-0.947 | 0.924 | 0.895-0.953 | 0.893 | 0.839-0.968 | 0.907 | ||
B | 0.663 | 0.198-0.919 | 0.704 | 0.5-0.854 | 0.819 | 0.814-0.837 | 0.520 | 0.5-0.579 | 0.653 | |||
SVM | Forward | Sex | A | 0.984 | 0.977-0.988 | 0.983 | 0.977-0.987 | 0.713 | 0.453-0.988 | 0.737 | 0.5-0.987 | 0.641 |
B | 0.981 | 0.93-0.988 | 0.981 | 0.934-0.987 | 0.817 | 0.488-0.988 | 0.799 | 0.45-0.987 | 0.782 | |||
Cyto Risk | A | 0.925 | 0.86-0.965 | 0.849 | 0.736-0.93 | 0.909 | 0.837-0.988 | 0.787 | 0.611-0.993 | 0.910 | ||
B | 0.950 | 0.831-0.977 | 0.916 | 0.66-0.986 | 0.935 | 0.849-0.977 | 0.924 | 0.704-0.986 | 0.935 | |||
Reverse | Sex | A | 0.603 | 0.547-0.698 | 0.563 | 0.5-0.667 | 0.986 | 0.977-0.988 | 0.985 | 0.974-0.987 | 0.587 | |
B | 0.510 | 0.453-0.547 | 0.500 | 0.458-0.549 | 0.500 | 0.407-0.599 | 0.499 | 0.401-0.6 | 0.505 | |||
Cyto Risk | A | 0.897 | 0.826-0.977 | 0.777 | 0.562-0.979 | 0.961 | 0.924-0.988 | 0.945 | 0.837-0.993 | 0.896 | ||
B | 0.789 | 0.535-0.814 | 0.487 | 0.339-0.5 | 0.874 | 0.767-0942 | 0.798 | 0.61-0.94 | 0.793 |