Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

Table 1 Characteristics of all pancreatic islet donors divided by sex

Phenotype	Males	Females	P -value
n	53	34
Age (years)	56 ± 11	58 ± 10	0.7
BMI (kg/m²)	25.6 ± 3.0	26.1 ± 4.1	0.7
Hba1c^a (%)	5.6 ± 0.5	5.6 ± 0.4	0.6
Stimulation index (SI^b)	6.2 ± 5.8	7.6 ± 5.3	0.03

Data is expressed as mean ± standard deviation. P-values are based on Mann-Whitney test. ^aData available for 45 males and 28 females. ^bData available for 48 males and 33 females. BMI, body mass index; HbA1c, hemoglobin A1c.

ISSN: 1474-760X