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Figure 4 | Genome Biology

Figure 4

From: Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets

Figure 4

Impact of sex on DNA methylation and/or expression in human pancreatic islets of selected candidate genes. (A) DUSP9, a candidate gene for type 2 diabetes, is located on the X chromosome and has numerous differentially methylated CpG sites between female and male human pancreatic islets. (B-D) Impact of sex on the DNA methylation level of CpG sites and gene expression of NKAP (B), APLN (C) and SPESP1 (D). Data are presented as mean ± standard error of the mean. Asterisks indicate q <0.05 for DNA methylation and P <0.05 for expression

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Genome Biology

ISSN: 1474-760X

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