Figure 4
From: TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator
TET1 and INSIG1 regulated expression of glucose metabolism genes induced by hypoxia in H1299 cells. (a,b) Induction of GLUT3, HK1, PGK2, PKM, and LDHA expression by hypoxia, which were regulated by TET1 and INSIG1. (c,d) Hypoxia-induced PGK1 expression was not regulated by TET1 or INSIG1. The asterisk (*) indicates statistical significance (P <0.05) between experimental (hypoxia) and control (normoxia) clones.