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Table 2 Putative tapeworm drug targets for which there is a TBLASTX hit in predicted S. erinaceieuropaei gene transcript (E-value >1e-10)

From: The genome of the sparganosis tapeworm Spirometra erinaceieuropaeiisolated from the biopsy of a migrating brain lesion

Putative E. multilocularis drug targets a TBLASTX E-value Percentage completeness b Percentage identity of match S. erinaceieuropaei gene ID
Thioredoxin glutathione reductase (TGR) 8e-77 28 73 SPER_0002850001
Fatty acid amide hydrolase 3e-59 39 50 SPER_0002366401
Adenine nucleotide translocator e-161 79 84 SPER_0000599901
Inosine 5′ monophosphate dehyrogenase 2e-81 42 79 SPER_0001958401
Succinate semialdehyde dehyrogenase 1e-54 25 68 SPER_0002970001
Ribonucleoside diphosphate reductase e-149 67 83 SPER_0000698501
Casein kinase II e-114 47 93 SPER_0000626801
Hypoxanthine guanine phosphoribosyltransferase 2e-35 57 43 SPER_0000257601
Glycogen synthase kinase 3 2e-69 50 84 SPER_0001364001
Proteasome subunit 4e-21 36 59 SPER_0002270001
Calmodulin 1e-94 100 98 SPER_0000219201
FK506 binding protein 3e-43 100 70 SPER_0000627901
UMP-CMP kinase 6e-24 40 73 SPER_0000808401
Na+/K+ ATPase 0 40 91 SPER_0000981501
Carbonic anhydrase II 3e-39 84 60 SPER_0002854501
NADH dehydrogenase subunit 1 3e-22 55 62 SPER_0000882501
Translocator protein 1e-26 95 44 SPER_0002949701
Elongation factor 2 0 81 70 SPER_0001150701
Cathepsin B (cysteine protease) 6e-93 62 61 SPER_0002586301
Dual-specificity mitogen activated protein 3e-54 27 86 SPER_0000571801
Purine nucleoside phosphorylase 3e-77 69 61 SPER_0000360401
  1. aExpressed in E. multilocularis larvae. bPercentage of E. multilocularis genes covered by alignment with S. erinaceieuropaei sequence.